美国国立卫生研究所分子医学方向博士后岗位

Postdoctoral Position in Molecular Medicine at NIH : Bethesda, MD, USA
Employer: National Heart, Lung and Blood Institute (NHLBI)
Location: Bethesda, MD, USA
Type: Postdoctoral
Posted: November 04, 2011
Expires: December 15, 2011

job description

Postdoctoral Position in Molecular Medicine at NIH

Department of Health and Human Services
National Institutes of Health
National Heart, Lung, and Blood Institute
Center for Molecular Medicine
A Postdoctoral position is available in Haiming Cao’s laboratory in the Center for Molecular Medicine at National Institutes of Health to study the molecular mechanisms of metabolic and inflammatory diseases. The Cao group is one of the first Earl Stadtman laboratories established at NIH, aimed at taking on high-risk, high-impact research (http://irp.nih.gov/careers/careers-in-action/science-the-stadtman-way, http://history.nih.gov/exhibits/stadtman/teachers_mentor.htm), and is supported by mouse transgenic, human induced pluripotent stem cell (iPS), high-throughput sequencing, advanced microscopy, animal surgery and bioinformatics core facilities. With an interdisciplinary research environment and strong intramural support, this position provides a unique opportunity for recent PhD or MD awardees to deepen and broaden their research profile for advancing to an independent academic career.

The Cao group is interested in understanding the molecular basis of obesity-induced disorders particularly diabetes, cardiovascular disease and inflammatory diseases with the goal of developing novel therapeutic interventions. Researches in the past decade, including Cao’s recent work (Cell 2008, Diabetes 2006, Cell Metabolism 2005), have established that dys-regulation of an intertwined network formed by metabolic and immune cells sits at the core of numerous pathological conditions. The Cao group investigates the inflammatory basis of metabolic diseases and the defective metabolism as a general cause of complex human diseases. The successful applicant is expected to study metabolic regulation by microRNAs, long non-coding RNAs and epigenetic regulators using diseased animal models, or develop a human iPS-based therapy for metabolic and inflammatory disorders. Research projects in the Cao lab emphasize bridging gaps between exciting new developments in molecular biology as well as accumulating Genome-Wide Association Studies (GWAS) data and human diseases of significant public health impact. More information on the Cao group is available at https://intramural.nhlbi.nih.gov/labs/LOMD/Pages/default.aspx.

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QUALIFICATIONS: Interested candidates should have obtained a PhD or MD degree within five years in Molecular Biology, Cell Biology, Biochemistry, Genetics, Physiology or a related discipline. The applicant should have record of delivering high-quality research using molecular biology approaches and mouse models, and should be capable of independently designing experiments and developing projects. In general, the quality of scientific thinking and intrinsic motivation are more important than experience in a specific research field.

SALARY/BENEFITS: This position is fully supported by NIH intramural fund and successful candidates will be offered competitive stipend/salary commensurate with experience and accomplishments.

TO APPLY: E-mail your Curriculum Vitae and at least 3 references to haiming.cao@nih.gov by December 15, 2011
HHS and NIH are Equal Opportunity Employers