美国爱荷华大学神经系统科学与新陈代谢博士后
2011-09-21 11:50 来源: 未知 作者: 颜墨
Job Description
| A postdoctoral or visiting scholar position will be available from early 2012 at the University of Iowa Carver College of Medicine and the Eagles Diabetes Research Center to investigate the neural control of feeding behavior and etiological mechanisms of obesity and eating disorders, such as anorexia nervosa, in genetic mouse models. Hypothalamic AgRP neurons are critical for regulation of feeding and body weight, as acute ablation of these cells in adult mice leads to anorexia and profound weight loss (see attached Review Article: Wu & Palmiter, Eur. J. Pharmacol., 2011). We demonstrated that such anorexic phenotype is fully reversible with the aid of a GABA-A receptor agonist and that GABA release from AgRP neurons onto neurons in the lateral parabrachial nucleus (PBN) is essential for maintenance of appetite and body weight (Wu et al., Cell, 2009). Therefore, we proposed that a novel hindbrain circuit and associated signaling pathways underlie neural adaptive control of anorexia and obesity through bi-directional modulation. This newly established laboratory is fully funded and well equipped, which permits utilization of cutting-edge technologies including, conditional gene targeting, viral-based gene transfer, immunocytochemistry, in vivo and ex vivo electrophysiology, functional profiling of novel drug targets, and CLAMS system-based metabolic and behavioral analysis. In addition, the University of Iowa Carver College of Medicine has outstanding core research (microscopy & imaging, histopathological, genomic, proteomic and transgenic) facilities, for the rapid advancement of research work. The ideal candidate will be a recent PhD and/or MD with a strong background in molecular biology and physiology. Knowledge of pharmacology, biochemistry, microbiology, electrophysiology, behavioral neurobiology, as well as experience with rodents would be an added advantage. The University of Iowa is an Equal Opportunity/Affirmative Action employer. Women and minorities are encouraged to apply. See below the ranking info of US Medical Schools for Research: http://grad-schools.usnews.rankingsandreviews.com/best-graduate-schools/top-medical-schools/research-rankings/page+2 To apply send your CV with publication list, statement of research interests, and name & contact info of three referees to Dr. Qi Wu at qiwu@uw.edu |
| Contact: | Qi Wu Pharmacology University of Iowa Iowa City, IA 52242 United States Email: qiwu  uw.edu |
|
When applying for this position, please mention you saw this ad on www.liuxuehr.com
Please also post your resume/CV in our resume database which is searched and viewed by many employers
and recruiters. This is a free service to all job seekers.
http://liuxuehr.com/reg_form.asp?what=in&agree=yes
1、声明：凡本网注明"来源：XXX"的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。如其他媒体、网站或个人从本网站转载使用，须保留本网站注明的“来源”，并自负版权等法律责任。作者如果不希望被转载或者联系转载等事宜，请与我们联系。
2、重要风险提示：如招聘单位在招聘过程中向求职者提出收取押金、保证金、体检费、材料费、成本费，或指定医院体检等，求职者有权要求招聘单位出具物价部门批准的收费许可证明材料，若无法提供相关证明，请求职者提高警惕，有可能属于诈骗或违规行为。
