美国弗吉尼亚生物信息学院酵母系统生物学博士

Postdoctoral Associate - Yeast Systems Biologist : Blacksburg, VA
Employer:  Virginia Bioinformatics Institute
Website:  http://www.vbi.vt.edu
Location: Blacksburg, VA
Type: Postdoctoral
Posted: September 08, 2011
Expires: November 07, 2011
Requisition number: 0110932

job description
*The Synthetic Biology group at Virginia Bioinformatics Institute (VBI) is involved in two collaborative research projects focused on the development of mathematical models of gene-protein regulatory networks controlling cell growth and division. Temporal organization of the budding yeast cell cycle has been studied from two vantage points: bottom-up models emphasize a protein regulatory network centered around cyclin-dependent protein kinases, whereas top-down models focus on a gene regulatory network governed by interrelated transcription factors. The first project is focused on unifying these two perspectives. The second project is focused on the development of stochastic models of the regulatory network controlling the cell cycle. Both projects are performed in close collaboration with experts in computer science, data mining, bioinformatics, and mathematical modeling. The successful candidate will be expected to contribute significantly to these two projects by being responsible for designing and performing experiments used to validate model predictions. These experiments will involve the development of a new collection of cell cycle mutants and their quantitative characterization by time-lapse microscopy. In addition, the successful candidate will be expected to prepare the results for publication and presentation, to help supervise graduate and undergraduate students, and to contribute to grant proposals.

Dependent on the qualifications of the successful candidate, the position will hold the research faculty rank of either Research Associate or Senior Research Associate. For more information on the university work ranks for research faculty, please review the Faculty Handbook located at http://www.provost.vt.edu/documents/FHB_2011.pdf.

The successful candidate will have -M.S. or bachelor’s degree with equivalent experience in molecular biology, genetics, systems biology, or related field (for the research faculty rank of Research Associate); or PhD or M.S. with equivalent experience in molecular biology, genetics, systems biology (for the research faculty rank of Senior Research Associate).
-Experience with yeast genetics (homologous recombination, crossing yeast strains, use of selection markers, genotyping); documented track record of relevant peer-reviewed publications; experience in molecular biology (plasmid design, plasmid constructions, cloning); excellent organizational and time management skills; ability to efficiently move between multiple tasks and adapt to changing requirements; and excellent communication skills in a diverse multicultural environment. For rank of Senior Research Associate, must have demonstrated experience leading an internal team (not necessarily in a supervisory role).

Preferences will be giving to candidates possessing knowledge or experience with time-lapse microscopy, proteomics techniques, familiarity with standard bioinformatics software, ability to run or develop data analysis scripts in Matlab, or aspiration to scientific independence.

Interested candidates should apply online at www.jobs.vt.edu, posting number 0110932 , and submit a cover letter, CV, and listing of professional references along with the required faculty application.

Candidates best meeting a combination of required qualifications and preferences will be invited to interview.

Compensation is commensurate with experience.

To learn more about VBI, please visit us as www.vbi.vt.edu

An Equal Opportunity / Affirmative Action Employer

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